Chronic food-restriction alters the expression of somatostatin and growth hormone-releasing hormone in the ovariectomised ewe.

Coexpression of gonadotropin inhibitory hormone with Agouti-related peptide in the neurons of arcuate nucleus of ewe hypothalamus

Introduction: Gonadotropin inhibitory hormone (GnIH) and Agouti-related peptide (AgRP) are orexigenic peptides expressed in the arcuate nucleus (Arc) of the hypothalamus in the ewe. In addition, effects of GnIH and AgRP on the regulation of gonadotropin releasing hormone secretion have been shown in some mammals. The objective of the present study was to investigate the coexpression of GnIH ...

Expression of gonadotropin inhibitory hormone in the preoptic area and its relation with phases of estrous cycle of ewe

Introduction: Gonadotropin inhibitory hormone (GnIH) has been known as a key inhibitor of the secretion of gonadotropin releasing hormone (GnRH). Ewe has estrous cycles comprising of follicular and luteal phases. Follicular phase is in turn divided into proestrous and estrous phases. Blood level of LH increases in follicular and decreases in luteal phases. The aim of the present study was to...

Comparison of Expression of Growth Hormone-Releasing Hormone and Its Receptor Splice Variant 1 in Different Stages of Endometriosis

Effect of intravenous injection of progesterone and its co-administration with growth hormone and morphine on ghrelin concentration in ewes with food restriction

Introduction: Ghrelin increases growth hormone secretion and food intake. Growth hormone (GH), steroid hormones and opioids are involved in the regulation of food intake. So, they may have a role in the regulation of ghrelin secretion. We determined the effect of intravenous injections of progesterone, GH and morphine or co-administration of these hormones on ghrelin concentration and body w...

Persistent changes in somatostatin and neuropeptide Y mRNA levels but not in growth hormone-releasing hormone mRNA levels in adult rats after intrauterine growth retardation.

A reduction in the availability of oxygen and nutrients across the placenta in the last trimester of pregnancy may lead to intrauterine growth retardation (IUGR) which, in turn, may cause a persistent postnatal growth failure. However, it is unknown whether this persistent growth retardation is centrally mediated through alterations in the components of the growth hormone (GH)-axis. We tested t...